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Comparing Protein Stability: ARGEN Application Note 001

Comparing the Stability of Protein Formulations with ARGEN Abstract Because ARGEN’s 16 experiments are fully independent, users can determine aggregation or degradation characteristics of protein formulations for all samples simultaneously, regardless of their individual time spans (some can take minutes, others can take weeks). When one sample is complete, another can immediately take its place....
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ARGEN_PEGS Boston 2018

Generating Aggregation Rates: ARGEN Technical Note 002

Generating Aggregation Rates to Determine Stability of Monoclonal Antibodies Background Static light scattering is widely used to measure the molar masses of molecules, particles and their aggregates under various solution conditions and compositions1. The ARGEN instrument has the capability to run 16 independent light scattering experiments simultaneously. It can monitor the change in both absolute...
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ARGEN_PEGS Boston 2018

Introduction to ARGEN: Technical Note 001

ARGEN: The Aggregation Rate GENerator that monitors protein and polymer stability Summary Fluence Analytics ARGEN platform continuously measures the light scattering from 16 independent solutions to assess the pharmaceutical stability of therapeutic proteins and natural polymers. ARGEN applies temperature and stirring stressors independently to each of the 16 sample cells, replicating the conditions of and...
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ACOMP

Monitoring the polymerization of PVP: ACOMP Application Note 001

Monitoring the effect of initiator concentration on molecular weight and intrinsic viscosity of polyvinyl pyrrolidone (PVP) using ACOMP Abstract Automatic Continuous Online Monitoring of Polymerization Reactions (ACOMP) was used to monitor the free radical polymerization of polyvinyl pyrrolidone (PVP) throughout the reaction. Two batch reactions were run at 1.5% and 2.5% initiator concentration to monitor...
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ACOMP

ACOMP Brochure

ACOMP Brochure: Realtime Monitoring of Polymerization Reactions ACOMP is Automatic Continuous On-line Monitoring of Polymerization reactions, a patented solution that continuously extracts, dilutes, and conditions a small stream of reactor contents for analysis by a variety of non-chromatographic and chromatographic methods throughout the entire reaction process. The system can directly measure macromolecular properties during production. This fundamental information...
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ARGEN_PEGS Boston 2018

ARGEN Brochure

ARGEN Brochure: Protein Stability Monitoring ARGEN by Fluence Analytics is the right instrument to assess the pharmaceutical stability of therapeutic proteins and general stability of natural polymer products. ARGEN allows for 16 independent experiments to run simultaneously, and each sample is measured continuously throughout the experiment, yielding extremely valuable kinetic sample stability data. ARGEN utilizes 16 completely independent cuvette sample...
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ACOMP

Introduction to ACOMP: Technical Note 001

ACOMP: The Automated System that allows Continuous Realtime Monitoring of Polymerization Reactions Abstract ​ ACOMP (Automatic Continuous Online Monitoring of Polymerization Reactions) is a patented product from Fluence Analytics that continuously monitors and characterizes polymers during polymerization or post-polymerization processing steps of laboratory or industrial scale polymer reactions. Beyond allowing the user to monitor polymerizations...
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