Understanding the thermal, chemical and mechanical stability and physical properties of polymers is essential for development success. The case studies below outline the experimental methodologies and data analysis using ARGEN™ to monitor polymer degradation and to characterize molecular weight as well as the effects of temperature, shear stress and solution conditions on the stability of...Read More
ACOMP was used to monitor the free radical polymerization of vinyl pyrrolidone using UV Absorption (UV), capillary viscometry and multi-angle light scattering (MALS). This technical note describes how ACOMP is used to monitor the polymerization of vinyl pyrrolidone under small changes in initiator concentrations.Read More
ACOMP Brochure: Realtime Monitoring of Polymerization Reactions ACOMP is Automatic Continuous On-line Monitoring of Polymerization reactions, a patented solution that continuously extracts, dilutes, and conditions a small stream of reactor contents for analysis by a variety of non-chromatographic and chromatographic methods throughout the entire reaction process. The system can directly measure macromolecular properties during production. This fundamental information...Read More
ARGEN Brochure: Protein Stability Monitoring ARGEN by Fluence Analytics is the right instrument to assess the stability of therapeutic biopolymers and natural polymer products. ARGEN users can conduct up to 16 independent experiments simultaneously. ARGEN generates real-time, continuous data throughout each experiment, yielding extremely valuable kinetic sample stability data. ARGEN’s 16 cuvette sample holders are...Read More
Biopharmaceutical companies isolate many types of proteins for use in experimental and therapeutic medicines. Unfortunately, when removed from their native environments, proteins become less stable. Unstable proteins are more prone to degradation from the primary stress mechanisms: mechanical and thermal (from manufacturing, storage and transport) and biological (from drug delivery). The challenge for biopharmaceutical companies...Read More
