In the high-stakes realm of biopharmaceutical research and development, understanding antibody stability is very important. Antibody stability is a multi-faceted concern that includes aspects of aggregation, degradation, and conformational integrity. Each of these potential problems can negatively impact antibody stability and the performance and manufacturability of biotherapeutics.Read More
Recent research on stress factors in monoclonal antibody development underscores the critical need for robust control strategies in monoclonal antibody drug substance production, focusing on the risks posed by various stress conditions during manufacturing. These stressors can lead to protein modifications, impacting both patient safety and product quality. ARGEN, by Yokogawa Fluence Analytics, is a...Read More
Characterizing colloidal stability is central to developing safe and efficacious protein-based therapeutics. To be viable, the target biotherapeutic must remain stable during production, storage, and patient delivery. The most insightful and successful techniques for monitoring and characterizing colloidal stability involve in-situ and real time analysis under modelled stress conditions. This permits the investigation of solution...Read More
ARGEN is a robust platform that can expand biopolymer formulation development efforts via novel data sets. The precision instrument addresses key challenges in biopolymer research by offering in-situ, real-time stability monitoring, manufacturing stress modelling, shelf-life determination, and rapid parallel analysis, leading to more efficient and effective formulation development.Read More
The ARGEN eBook discusses the key indicators of biopolymer instability, the importance of accelerating development times, and how ARGEN expedites the development of stable biopolymers.Read More
