Tag

DNA

New Technique to Monitor DNA Release and Capsid Protein Stability

This dynamic webinar offers insights into characterizing the stability of an engineered adeno-associated virus (AAV) serotype under moderate thermal stress and physiological solution conditions using light scattering measurements. This webinar highlights experiments that investigated and characterized the effects of thermally-induced perturbations on DNA ejection from a proprietary AAV vector. The experiments were conducted at three...
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DNA Released by Adeno Associated Virus Alters Aggregation

The academic research partner of Yokogawa Fluence Analytics, Tulane PolyRMC, partnered with Spark Therapeutics on a new peer-reviewed article in Biomacromolecules that highlights the degradation of adeno-associated virus (AAV) under moderate thermal stress (30−53°C) and in physiological solution (pH7.2, 180 mM NaCl). 
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