Determine the Stability of Biologics This peer review article from American Pharmaceutical Review describes new tools for determining the stability of biologics, including ARGEN by Fluence Analytics, that not only have low sample requirements but also generate precise and reproducible data to effectively implement an advanced design of experiments approach. This article uses a real case...Read More
Protein aggregation has presented biopharmaceutical scientists with constant difficulties during formulation development. Historically, batch-based methods such as SEC, HPLC and other aggregation detectors offer incomplete solutions because they do not provide scientists with realtime kinetic data on protein stability nor insight into the mechanisms of protein aggregation. ARGEN, an instrument by Fluence Analytics, adds a powerful tool to the protein scientist’s arsenal. ARGEN is a light scattering instrument...Read More
A critical component of the biopharmaceutical development process is the creation of a formulation to protect proteins from various mechanical and thermal stressors that occur during manufacturing, storage and transport. In non-optimized formulations, stressors cause protein degradation which can render the biopharmaceutical ineffective and possibly harmful to patients. For this reason, researchers are starting to...Read More
