Tag

formulation development
ARGEN_PEGS Boston 2018

Formulating Four Peptides: ARGEN Application Note 005

Formulation of Four Peptide Solutions in 15 Days Background Custom designed oligopeptides are an increasingly accessible option in peptide-based technologies for pharmaceuticals. Following their synthesis, peptides are often subjected to HPLC purification and synthetic modification, which can require the use of non-aqueous media or salts requiring later removal. During the production of pharmaceutical peptides, spoilage...
Read More

ACOMP and ARGEN take center stage at 255th ACS National Meeting & Exposition in New Orleans

Fluence Analytics, a manufacturer of realtime monitoring solutions for polymer and biopharmaceutical companies, will present two session talks and have an exhibition booth (#1111) during the American Chemical Society’s (ACS) 2018 Spring National Meeting & Exposition. The 255th National Meeting is taking place in New Orleans, LA from March 18-22. The first Fluence Analytics presentation...
Read More
ARGEN_PEGS Boston 2018

Formulation Development: ARGEN Application Note 002

Formulation Development with ARGEN Abstract Formulations are developed in the biopharmaceutical space as a set of solution conditions that lead to the highest stability of a therapeutic substance such as an antibody protein or peptide.  The solution conditions that generally affect the stability of the solute are solvent choice, ionic strength, pH, excipient, surfactant and...
Read More
FA_Product_ARGEN

Comparing Protein Stability: ARGEN Application Note 001

Comparing the Stability of Protein Formulations with ARGEN Abstract Because ARGEN’s 16 experiments are fully independent, users can determine aggregation or degradation characteristics of protein formulations for all samples simultaneously, regardless of their individual time spans (some can take minutes, others can take weeks). When one sample is complete, another can immediately take its place....
Read More
ARGEN - Stability of Biologics

Automated & Rapid Way to Asses Quality & Stability of Biologics

Determine the Stability of Biologics This peer review article from American Pharmaceutical Review describes new tools for determining the stability of biologics, including ARGEN by Fluence Analytics, that not only have low sample requirements but also generate precise and reproducible data to effectively implement an advanced design of experiments approach. This article uses a real case...
Read More
ARGEN_PEGS Boston 2018

Introduction to ARGEN: Technical Note 001

ARGEN: The Aggregation Rate GENerator that monitors protein and polymer stability Summary Fluence Analytics ARGEN platform continuously measures the light scattering from 16 independent solutions to assess the pharmaceutical stability of therapeutic proteins and natural polymers. ARGEN applies temperature and stirring stressors independently to each of the 16 sample cells, replicating the conditions of and...
Read More
Translate »