Tag

Protein Formulation Stability

Fluence Analytics Brochure

Fluence Analytics Brochure: realtime data. realtime optimization. Fluence Analytics is a manufacturer of industrial and laboratory monitoring solutions that produce continuous data streams. The company has two product lines, ACOMP and ARGEN. Combined with powerful, proprietary analytical tools, the confluence of data from the company’s measurements enable realtime optimization leading to improved process control and...
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Fluence Analytics to exhibit at PEGS Boston: The Essential Protein Engineering Summit

  PEGS: The Essential Protein Engineering Summit is one  of the industry’s preeminent events for anyone involved in biotherapeutic drug development. The annual conference is always held in Boston, and this year’s summit will take place at the Seaport World Trade Center from April 30 – May 4. At booth number 438, Fluence Analytics will...
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Kinetic Analysis of Protein Stability & Oligomeric State Transitions of Human Insulin

These experiments demonstrate the utility of ARGEN™ to define oligomeric states and transitions of Human Insulin under thermal stress. Time to dimerization and time to tetramerization measurements permitted the characterization of a stable dimer species, as well as insights into the mechanisms and kinetics of higher order oligomer formation. Whereas, SEC allows the characterization of...
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Introduction to ARGEN

Rapid Analysis of Protein Formulation Stability ARGEN, by Fluence Analytics, adds another powerful tool to the protein scientist’s arsenal. ARGEN is a light scattering instrument with 16 independent sample cells that can test for protein aggregation while stressing samples under multiple conditions including chemical, mechanical and thermal…all in real time and accelerating protein formulation stability!...
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Automated & Rapid Way to Assess Quality & Stability of Biologics

Determine the Stability of Biologics This peer review article from American Pharmaceutical Review describes new tools for determining the stability of biologics, including ARGEN by Fluence Analytics, that not only have low sample requirements but also generate precise and reproducible data to effectively implement an advanced design of experiments approach. This article uses a real case...
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Fluence Analytics to exhibit and present new developments in use of light scattering to determine aggregation rates at PepTalk 2018

PepTalk, one of the largest annual conferences for protein researchers in the world, will take place from January 8-12, 2018 at the Hilton San Diego Bayfront. Fluence Analytics is attending the 17th annual conference and will showcase ARGEN at exhibition booth number 315. The booth will feature an ARGEN system with software demos, and members of...
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Biopolymer Characterization & Polymer Degradation

Understanding the thermal, chemical and mechanical stability and physical properties of polymers is essential for development success. The case studies below outline the experimental methodologies and data analysis using ARGEN™ to monitor polymer degradation and to characterize molecular weight as well as the effects of temperature, shear stress and solution conditions on the stability of...
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ARGEN Brochure

ARGEN Brochure: Protein Stability Monitoring ARGEN by Fluence Analytics is the right instrument to assess the stability of therapeutic biopolymers and natural polymer products. ARGEN users can conduct up to 16 independent experiments simultaneously. ARGEN generates real-time, continuous data throughout each experiment, yielding extremely valuable kinetic sample stability data. ARGEN’s 16 cuvette sample holders are...
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Fluence Analytics Announces ARGEN Product Launch

New Instrument Continuously Analyzes Protein and Natural Polymer Aggregation (New Orleans, LA, U.S.) ‒ Fluence Analytics, a manufacturer of realtime, industrial and laboratory monitoring systems, today announced the launch of ARGEN, a patented protein and polymer stability monitoring product. By utilizing continuous light scattering measurements, ARGEN yields a unique information stream which reduces discovery and...
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Fluence Analytics Webinar – Rapid Analysis of Protein Formulation Stability

Protein aggregation has presented biopharmaceutical scientists with constant difficulties during formulation development. Historically, batch-based methods such as SEC, HPLC and other aggregation detectors offer incomplete solutions because they do not provide scientists with realtime kinetic data on protein stability nor insight into the mechanisms of protein aggregation. ARGEN, an instrument by Fluence Analytics, adds a powerful tool to the protein scientist’s arsenal. ARGEN is a light scattering instrument...
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