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Protein Formulation Stability
ARGEN

Application Note: ARGEN 002

Formulation Development with ARGEN Abstract Formulations are developed in the biopharmaceutical space as a set of solution conditions that lead to the highest stability of a therapeutic substance such as an antibody protein or peptide.  The solution conditions that generally affect the stability of the solute are solvent choice, ionic strength, pH, excipient, surfactant and...
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ARGEN

Application Note: ARGEN 001

Comparing the Stability of Protein Formulations with ARGEN Abstract Because ARGEN’s 16 experiments are fully independent, users can determine aggregation or degradation characteristics of protein formulations for all samples simultaneously, regardless of their individual time spans (some can take minutes, others can take weeks). When one sample is complete, another can immediately take its place....
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ARGEN Webinar

Webinar: Introduction to ARGEN

Rapid Analysis of Protein Formulation Stability ARGEN, by Fluence Analytics, adds another powerful tool to the protein scientist’s arsenal. ARGEN is a light scattering instrument with 16 independent sample cells that can simultaneously test for protein aggregation utilizing light scattering while stressing samples under multiple conditions including chemical, mechanical and thermal…all in real time and...
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ARGEN

Automated & Rapid Way to Asses Quality & Stability of Biologics

This peer review article from American Pharmaceutical Review describes new tools, including ARGEN by Fluence Analytics, that not only have low sample requirements but also generate precise and reproducible data to effectively implement an advanced design of experiments approach. This article uses a real case study using an IgG 1 antibody to illustrate how to properly...
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PepTalk logo

Fluence Analytics to exhibit and present new developments in use of light scattering to determine aggregation rates at PepTalk 2018

PepTalk, one of the largest annual conferences for protein researchers in the world, will take place from January 8-12, 2018 at the Hilton San Diego Bayfront. Fluence Analytics is attending the 17th annual conference and will showcase ARGEN at exhibition booth number 315. The booth will feature an ARGEN system with software demos, and members of...
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ARGEN

Technical Note: ARGEN 001

ARGEN: The Aggregation Rate GENerator that monitors protein and polymer stability Summary Fluence Analytics ARGEN platform continuously measures the light scattering from 16 independent solutions to assess the pharmaceutical stability of therapeutic proteins and natural polymers. ARGEN applies temperature and stirring stressors independently to each of the 16 sample cells, replicating the conditions of and...
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ARGEN

ARGEN Brochure

Protein Stability Monitoring ARGEN by Fluence Analytics is the right instrument to assess the pharmaceutical stability of therapeutic proteins and general stability of natural polymer products. ARGEN allows for 16 independent experiments to run simultaneously, and each sample is measured continuously throughout the experiment, yielding extremely valuable kinetic sample stability data. ARGEN utilizes 16 completely independent cuvette sample holders, and...
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ARGEN

Fluence Analytics Announces ARGEN Product Launch

New Instrument Continuously Analyzes Protein and Natural Polymer Aggregation (New Orleans, LA, U.S.) ‒ Fluence Analytics, a manufacturer of realtime, industrial and laboratory monitoring systems, today announced the launch of ARGEN, a patented protein and polymer stability monitoring product. By utilizing continuous light scattering measurements, ARGEN yields a unique information stream which reduces discovery and...
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fluence analytics webinar

Fluence Analytics Webinar – Rapid Analysis of Protein Formulation Stability

Protein aggregation has presented biopharmaceutical scientists with constant difficulties during formulation development. Historically, batch-based methods such as SEC, HPLC and other aggregation detectors offer incomplete solutions because they do not provide scientists with realtime kinetic data on protein stability nor insight into the mechanisms of protein aggregation. ARGEN, an instrument by Fluence Analytics, adds a powerful tool to the protein scientist’s arsenal. ARGEN is a light scattering instrument...
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ARGEN

Dr. Danny Chou to Present New Study Results at Bioprocessing Summit

New Study Involves Increased Protein Stability Using APMT’s ARGEN Product (New Orleans, LA, U.S.) ‒ Advanced Polymer Monitoring Technologies (APMT) has partnered with Dr. Danny Chou of Compassion BioSolution, LLC and other researchers on a multi-collaborator study involving various measurement techniques, including APMT’s ARGEN product. Dr. Chou will present the results of this study on August 15-16,...
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